International Journal of Educational Research and Development

International Journal of Educational Research and Development


International Journal of Educational Research and Development
International Journal of Educational Research and Development
2021, Vol. 3, Issue 3
Possible role of the nuclear factor kappa beta (NF-{kappa} B) in the development of retained placenta

Sohair A Moustafa

Abundant evidence suggests that NF-{kappa} B has a role in the physiology and pathophysiology of labour. The current study was undertaken to test the hypothesis that NF-{kappa} B may play a role in the pathogenesis of retained placenta (RP) in buffalo. Results of the present study revealed that there is a significant decrease in the serum level of NF-{kappa} B in buffalos with retained placenta (BRP) compared with its level in buffalos with normal placental release (NPR). Significant decreases in the serum levels of TNF-α and NO were also observed in BRP. Meanwhile, PGE2 level was significantly increased in the serum of BRP while the serum level of oxytocin (OT) was not significantly changed in both groups. The possible effect of the decreased activity of NF-{kappa} B in reducing myometrial contraction and in causing immunosuppression as two basic mechanisms in the etiology of RP was discussed.
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How to cite this article:
Sohair A Moustafa. Possible role of the nuclear factor kappa beta (NF- B) in the development of retained placenta. International Journal of Educational Research and Development, Volume 3, Issue 3, 2021, Pages 45-48
International Journal of Educational Research and Development International Journal of Educational Research and Development